An Intimate Room. A Big Night Out.
Seratonic Venue & Lounge is downtown Greenville’s go-to for live music and entertainment, cocktails, and nights that feel personal. Elevated and designed for connection, it’s an unparalleled setting between performer and audience, with a front-row feel all night long. Choose VIP tables or lounge-style couch seating with food and beverage table service or go General Admission for the energy—every show comes with immersive production and up-close moments from every angle.
Because Seratonic isn’t just a name—it’s a feeling. The chemistry of happiness meets the texture of sound. And it hits different here.
Get early access to tickets, exclusive offers, and upcoming concerts and events at Seratonic Venue & Lounge—Greenville’s intimate live music venue where artists and audiences connect up close.








Seratonic Venue & Lounge
315 South Main Street, Greenville, SC 29601
seratoniclounge.com
AC Hotel Greenville Partnerships
Seratonic Venue & Lounge © 2026.
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tajin, cilantro (GF, Veg)
chorizo, tomato, cilantro, yuca (GF)
stout mustard, paprika (Veg)
pineapple, soy glaze, sesame seed (GF, Veg)
buffalo sauce, black truffle, pecorino (GF)
smoked gouda, crispy onion, horseradish aioli
creole mustard, pickled onion
cinnamon sugar, caramel, dark chocolate (Veg)
lady finger, espresso, cocoa powder (Veg)